Nano Raman with TERS & SERS
SERS - Surface Enhanced Raman Spectroscopy
SERS enables direct and rapid trace level detection for toxins, viruses, bacteria, cancer, antibody, DNA and RNA at clinical sites, without the need of preprocessing of blood or other samples.
Raman spectra could be detected from 20 μL of 10 μM R6G sprinkled onto glass coated with silver nanowires as SERS. However, the same 10 μM R6G couldn't be detected without the use of SERS.
3D RCW SERS improves the discriminant accuracy.
With the 3D random crossed wire woodpile (RCW) used as a SERS chip for direct and rapid detection of pesticides (a) thiram, (b) carbaryl, (c) paraquat, and (d) fipronil with rational detecting ranges (nanomole), the discriminant accuracy of Raman spectra is improved.
« A 3D Plasmonic Crossed-Wire Nanostructure for Surface-Enhanced Raman Scattering and Plasmon-Enhanced Fluorescence Detection »
STM Based Nano Raman (TERS)
The tip enhanced Raman spectroscopy (TERS), enhanced by the « hot spot » effect created by the nano-scale tip apex, could measure the originally undetectable Raman signals of nanoscale structures or trace elements. Our nano Raman system based on STM also practically improves the Raman mapping resolution from 1 µm to 10 nm.
Our STM based nano Raman sytem will be released in 2022. Under development are the AFM / SNOM modules that could be integrated in the same system as well as the inline and high vacuum system for semiconductor use.